Chromatography and electrophoresis are established analytical techniques ideally suited for analyzing complex mixtures of biochemical, clinical, biological, environmental, and geological origin. The broad acceptance of these techniques is a direct result of their unparalleled separation power, sensitivity, speed, and ease of automation. The course covers the fundamentals of separation science and also surveys a broad range of chromatographic and electrophoretic techniques. The course comprises 30 hours of lectures along with 4 practical exercises.
The course covers the basics theory of NMR spectroscopy, including the effects of radiofrequency pulses, relaxation, multipulse, and heteronuclear experiments. 1D and 2D NMR methods are applied to solving chemical problems such as structure and conformation. Quantification by NMR spectroscopy and the coupling of NMR to HPLC systems is also discussed. Mass spectrometry, considered to be one of the most versatile analytical techniques, finds widespread use in chemistry, biochemistry, pharmaceutical chemistry, health science, archaeology, forensic science, environmental science, and space exploration. This module overviews the basic concepts of mass spectrometry and a broad range of commonly used techniques. Applications of these techniques in chemistry and biochemistry are presented and discussed. Attending this module does not require any previous knowledge of mass spectrometry.
In this module, you will learn how modern analytical methods are applied to diverse areas such as clinical diagnostics, forensic toxicology, molecular biology, molecular genetics, and clinical nano-materials. The course includes HPLC in bioanalysis; electrophoresis in clinical practice; proteomics; DNA and molecular genetics and drug analysis in biofluids.
The optical spectroscopy course covers the physical basis of infrared, Raman, NIR, UV-Visible, and fluorescence spectrophotometry, the design and mode of operation of the instruments and applications of the techniques are covered in some detail. It is supported by three laboratory exercises. Atomic spectrometry comprises the most powerful and widely used methods for the determination of elements. The course covers atomic absorption (flame and furnace), atomic emission from the inductively coupled plasma (ICP), elemental mass spectrometry, and x-ray fluorescence.
The projects offered on this novel research project cover a wide range of fields, and you may choose between working in one of our ‘wet’ research laboratories, carrying out a biocomputational project, or, if suitable, conducting research at your place of work.